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Modification of Polysulfone Membrane by Low Temperature Plasma Technology and Its Application in Membrane Oxygenator

Authors： Yin Hai-yan 1, Liu Yao-dong 1,Huang Xin1，Lv Quan1, Yu Wen-kui 2, Li Lei 1

Units： 1.Department of Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P.R.China; 2. Medical School, Nanjing University, Nanjing 210093, P.R.China

KeyWords： Sf membrane oxygenator; low temperature plasma; contact angle; adsorption of bovine serum albumin

ClassificationCode：TB324

year,volume(issue):pagination： 2014,34(4):50-55

Abstract：

In this study, polysulfone(PSF) asymmetric membranes used for membrane oxygenator were modified by low temperature plasma technology(LTPT) to improve their hemocompatibility. PSF membrane surface was activated by LTPT, and then polyethylene glycol (PEG) and heparin were grafted onto membrane surface. The effects of PEG molecular weight and plasma treatment conditions on modification results were investigated thoroughly. It was demonstrated through experiments of membranes preparation that the modified membranes had the optimal results such as smaller contact angles and less adsorption of bovine serum albumin when the molecular weight of polyethylene glycol is 6000, the plasma power is 150 watts, the treatment time is 2 minutes and the process gas is argon(Ar). Besides, experimental results of gas-liquid transfer indicated that the modified membranes retained almost the same gas transmission performance as unmodified ones, which proved to reach the standard of medical membrane oxygeantor mainly

Funds：

江苏省自然科学基金面上项目（BK2012727）

AuthorIntro：

殷海燕（1989—），男，江苏省南通市人，硕士研究生，研究方向为人工肺用膜材料

Reference：

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