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Research on plasma modification of polysulfone hollow fiber membrane for artificial lung

Authors： LiuYaodong 1,Huang Xin1，Wang Weiping1, YuWenkui 2, Li Lei 1*

Units： 1.Department of Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P.R.China; 2. Medical School, Nanjing University, Nanjing 210093, P.R.China

KeyWords： Polysulfone; Artificial lung; Plasma; Heparin sodium;Blood Compatibility

ClassificationCode：TQ028.8

year,volume(issue):pagination： 2015,35(4):35-39

Abstract：

AA and heparin were grafted onto the surface of PSfhollow fiber membranesfor artificial lung by low temperature plasma technology to improvetheir blood compatibility. The contact angle and grafting degree of modified PSf membrane was optimized by being treated for process time of 60s with Aratmosphere at power of 40 W.The amounts of adsorbed BSA and adhesive platelets on the grafted PSf membranes decreasedsignificantly.Besides, the experimental results of gas-liquid transfer indicated that the modified membrane retained excellent gas permeation flux of PSfmembrane, which could achievebasically the gas exchange transmission capacity of artificial lung.

Funds：

江苏省自然科学基金面上项目（BK2012727）

AuthorIntro：

刘耀东（1990—），男，安徽省铜陵人，硕士研究生，研究方向为膜分离技术；李磊，男，副教授，

Reference：

[1] JF Blanco，J Sublet，QT Nguyen, et al.Formation and morphology studies of different polysulfones-based membranes made by wet phase inversion process[J]. J Membrane Sci，2006，283（1-2）：27-37。
[2]俞三传，金可勇，高从堦.高性能聚砜支撑膜研制[J]. 膜科学与技术，1999，19（6）：45-47+55
[3]K Ota. Advances in artificial lungs[J]. J Artif Organs，2010，13（1）：13-16
[4]王丽红,陈欢林.改善生物医用高分子膜表面血液相容性的PC技术[J].膜科学与技术，2006,26（3）:90-94.
[5]JM Grace，LJ Gerenser.Plasma Treatment of Polymers[J].J DisperSciTechnol，2003,24（3-4）:305-341.
[6]陈剑，李继定，王鼎，等.低温等离子体接枝改性PVDF膜[J].膜科学与技术，2007,27(1): 23-26+31
[7]K Akamatsu，T Furue，F Han，S Nakao，et al.Plasma graft polymerization to develop low-fouling membranes grafted withpoly(2-methoxyethylacrylate)[J]. Sep PerifTechnol，2013,102（4）：157–162
[8]F Taraballi, S Zanini, C Lupo. Amino and carboxyl plasma functionalization of collagen films for tissue engineering applications[J]. J Colloid InterfSci，2103,394（15）:590-597.
[9]F Kara，EA Aksoy，Z Yuksekdag，et al. Synthesis and surface modification of polyurethanes with chitosan for antibacterial properties[J]. CarbohydPolym，2014,112（4）:39-47
[10]吕权，殷海燕，虞文魁等，膜式氧合器中聚砜非对称膜的制备及表征[J],膜科学与技术，2013，33(5):25-29.
[11]RQ Kou, ZK Xu, HT Deng，et al. Surface modification of microporouspolypropylene membranes by the grafting ofpoly(γ-stearyl-L-glutamate)[J].
[12]ZM Liu, ZK Xu,JQ Wang, et al. Immobilization of bovine serum albumin onto porous polyethylene membranes using strongly attached polydopamine as a spacer[J]. Colloid Surface B,2011,86（1）:111-118.
[13]殷海燕，刘耀东，黄鑫等，聚砜膜的低温等离子体改性及其在膜式氧合器的应用[J]，膜科学技术，2014，34(4):50-55.
[14]B ?íhová. Biocompatibility of biomaterials: hemocompatibility, immunocompatiblity and biocompatibility of solid polymeric materials and soluble targetable polymeric carriers[J]. Adv Drug Deliver Rev，1996，21（2）：157-176.

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