膜科学与技术

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Preparation and characterization of Levofloxacin/polyvinylidene difluoride blend ultrafiltration membrane with antibacterial property

Authors： LIAO Xiangjun，LIU Hailong

Units： (School of Environmental Science and Resources，Shanxi University，Taiyuan 030006，China)

KeyWords： levofloxacin；PVDF；hydrophilicity；anti-pollution；antibacterial

ClassificationCode：TQ028.8

year,volume(issue):pagination： 2018,38(5):38-46

Abstract：

Levofloxacin(LVFX)/polyvinylidene difluoride(PVDF) blend ultrafiltration membrane was prepared by immersion-precipitation phase inversion method. The effects of levofloxacin as additive on membrane structure and properties were investigated. Fourier transform infrared spectroscopy (FTIR)、scanning electron microscope (SEM) and contact angle were used to characterize the existence of levofloxacin on PVDF membrane and its influence on membrane morphology and hydrophilicity. The antifouling performance and antimicrobial activity of LVFX/PVDF blend membrane were evaluated respectively by static adsorption of BSA, decay of circulating flux, inhibition zone and inhibition rate. The results showed that levofloxacin was present on the membrane stably. With the increase of the levofloxacin ratio, the contact angle of the blend membrane decreased from 77.7°to 62.1°, the hydrophilicity of the membrane was enhanced. The BSA static adsorption capacity decreased while the flux recovery rate increased, the irreversible pollution index decreased to 11.8% when the addition ratio of LVFX was 0.6%, which possessed the best antifouling ability. The inhibition zone was formed when the addition ratio of LVFX was 0.3%. When the adding ratio was 0.6%, the antibacterial rate could reach 92.3%, showing excellent antibacterial properties. In addition, the blend membranes was regenerated after run for a period of time, still maintained a good antibacterial effect.

Funds：

家自然科学基金项目（51179099/E090301）；山西省重点研发计划项目（201603D321007）；山西省科技攻关项目（20140313003-3）；山西省留学回国人员科技活动择优资助项目（2014）；山西省回国留学人员科研资助项目（2015-004）

AuthorIntro：

第一作者简介：廖祥军（1995-），男，山东泰安人，硕士研究生，从事膜材料制备及其应用研究，E-mail：xiangjunliao@yeah.net. *通讯作者，E-mail：hlliu827@aliyun.com

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