膜科学与技术

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ClassificationCode：O652.6；TQ028.8

year,volume(issue):pagination： 2020,40(2):1-5

Abstract：

Using vancomycin and 1,6-diisocyanatehexane as monomers, an enantioselective composite membrane was prepared by interfacial polymerization on a polyethersulfone support. After the composite membrane was mounted in a home-made device of membrane chromatography for high performance liquid chromatography, the enantioseparation of D,L-phenylglycine was carried outed by the chiral membrane chromatography. By optimizing the injection volume, the flow rate, the constituent of mobile phase, the size of the membrane, the layer numbers of the membrane, over 5.66 of separation factor (α) and 0.66 of resolution (Rs ) could be obtained, respectively. The advantage of the method is the ability to separate and prepare chiral compounds in an aqueous environment, which is rare in chromatographic chiral separation.

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国家自然科学基金地区项目“界面聚合手性高分子复合膜研究”（21365025）、国家自然科学基金重大研究计划项目“手性高分子固膜的精准结构调控和制备研究”（91856123）

AuthorIntro：

第一作者简介：艾萍（1962-），女，四川高县人，教授，从事手性分离研究，E-mail：aipdeyx@aliyun.com 通讯作者：E-mail：yuan_limingpd@126.com

Reference：

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