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Research progress of vapor permeation membrane separation in pharmaceutical and chemical industry |
| Authors： LIU Qin1, WANG Yan1, WU Siyuan1, LI Wancheng1, WU Bo1, LI Chuanrun1,2 |
| Units： 1. Pharmaceutical Engineering Technology Research Center, School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China; 2. Anhui Province Key Laboratory of Pharmaceutical Preparation Technology and Application, Hefei 230012, China |
| KeyWords： membrane; vapor permeation; gas; mixtures; separation |
| ClassificationCode：TQ028.8 |
| year,volume(issue):pagination： 2025,45(1):185-196 |
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Abstract： |
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Vapor permeation is one of the new membrane separation technologies in recent years. Mixture in the form of vapor feed, by the chemical gradient (pressure, temperature) as the driving force, the use of each component in the membrane dissolution and diffusion properties of the difference between the membrane to achieve the separation of the mixture of membrane technology. Vapor permeation membrane separation process is directly in contact with vapor, pollution is small, not only simplifies the process flow, but also reduces energy consumption. Simple operation can be effectively combined with other separation technologies such as distillation, adsorption, etc., to form an integrated separation system to improve the overall separation efficiency and selectivity. At present, vapor permeation industrial equipment can realize the dehydration of alcohols, ethers, ketones, esters, hydrocarbons and other systems, with a yield of more than 99%. Vapor permeation coupled with hydrolysis reaction; the conversion rate of ethyl lactate was nearly 100%. Therefore, in the petrochemical industry, traditional Chinese medicine, water treatment and other industrial fields have broad application prospects. In this paper, commonly used vapor permeation membrane materials were discussed. The current status of the application of vapor permeation membrane separation technology was summarized. The value of the vapor permeation membrane coupling process was summarized; the prospects of the vapor permeation membrane separation technology were outlook. To provide reference for the research of steam permeation membrane separation technology, with a view to ultimately realizing the efficient comprehensive utilization of vapor permeation membrane in the field of pharmaceutical and chemical industry. |
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Funds： |
| 国家重点研发计划项目（2022YFB3805100）； 国家自然科学基金项目（22478007）； 安徽省高校自然科学研究重点项目（2023AH050728） |
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AuthorIntro： |
| 刘琴（1998-），女，湖北应城人，硕士生，研究方向为制药过程传质与分离. |
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Reference： |
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