膜科学与技术

Position：Home >> Abstract

Research on the deacidification and organic matter recovery of glucosamine fermentation waste liquid by diffusion dialysis-electrodialysis coupling

Authors： WANG Yuqi, CAO Donghai, LIU Rui, CHEN Shuting, DONG Liming, YU Suping

Units： Key Laboratory of Cleaner Production and Integrated Resource Utilization of China National Light Industry, State Environmental Protection Key Lab of Food Chain Pollution Control, Beijing Technology and Business University, Beijing 100048, China

KeyWords： diffusion dialysis; electrodialysis; fermentation waste liquid; recovery of organic matter

ClassificationCode：X703； TQ028

year,volume(issue):pagination： 2026,46(1):140-153

Abstract：

For glucosamine fermentation waste liquid with strong acidity and a large amount of residual organic matter, this study employed diffusion dialysis (DD) to pretreat the waste liquid and remove part of acid. Subsequently, electrodialysis was used to further deacidify the zero-stage, first-stage and second-stage diffusion dialysis treated liquid and recover the organic matter at the same time. A life cycle assessment was also conducted. Results showed that DD removed approximately 50% of the acid. The high concentration of glucosamine hydrochloride (GlcN·HCl) caused the strongest inhibition of H+ mass transfer due to electrostatic interference, reducing the mass transfer coefficient by 61.1%. The ED process achieved an acid removal efficiency of 99.9%, with combined recovery of GlcN·HCl in the concentrate and electrode compartment exceeding 80%. The GWP value of the two-stage DD-ED process was 7.40×10-2 kg CO2 eq/L lower than that of the zero-stage DD-ED process. Thus, the multi-stage DD-ED process effectively saved energy, separated acid from organic matter in waste liquid, and provided theoretical support for industrial application.

Funds：

国家自然科学基金项目(41861124004)

AuthorIntro：

王玉祺（2001-），女，河北石家庄人，硕士研究生，主要研究方向为清洁生产与资源的综合利用

Reference：

[1]Ahuja V, Bhatt A K, Sharma V, et al. Advances in glucosamine production from waste biomass and microbial fermentation technology and its applications[J]. Biomass Convers Biorefin, 2025, 15(2) : 1643-1665.
[2]山东润德生物科技有限公司.一种制备氨基葡萄糖盐酸盐的方法:中国, CN201910658842.9[P]. 2019-09-20.
[3]李福勤, 王世奕, 梁桢, 等. 扩散渗析-纳滤分离工艺资源化再生钢铁酸性脱硫废水的试验研究[J]. 工业水处理,2024， 44(11): 1-16.
[4]张满, 赵立新, 冯炘, 等. 扩散渗析法回收废铅膏电解液中硫酸的实验研究[J]. 天津理工大学学报,2024, 40(3) : 135-139.
[5]于传平. 氨基葡萄糖盐酸盐结晶热力学与晶体形态研究[D]. 济南：山东建筑大学, 2024.
[6]Zhou X, Liu Q, Chen X, et al. Enzymatic hydrolysis of chitinous wastes pretreated by deep eutectic solvents into N-acetyl glucosamine[J]. Polym Degrad Stab, 2024, 227: 110907.
[7]Chen Q, Zhang G, Liu R, et al. Integration of concentration and electro-driven membrane system for effective water-saved acid recycling performance[J]. Resour Conserv Recycl, 2023, 191: 106885.
[8]张莉, 娄玉峰, 蓝靖, 等. 膜集成工艺在处理铝箔腐蚀废酸中的应用研究[J]. 离子交换与吸附,2024, 40(4) : 330-338.
[9]Nazir A, Khan K, Maan A, et al. Membrane separation technology for the recovery of nutraceuticals from food industrial streams[J]. Trends Food Sci Technol, 2019, 86: 426-438.
[10]Dai Z, Chen C, Li Y, et al. Hybrid donnan dialysis-electrodialysis for efficient ammonia recovery from anaerobic digester effluent[J]. Environ Sci Ecotechnol, 2023, 15: 100255.
[11]Mir N, Yuzer B, Bicer Y. Photo-electrodialysis for brackish water desalination: A life cycle sustainability assessment from experimental insights[J]. Energy Technol, 2025, 13(9): 2402079.
[12]杨露, 祝海涛, 吴雅琴, 等. 电渗析用于高含盐葡萄糖溶液的脱盐处理[J]. 水处理技术,2021, 47(5): 47-51, 56.
[13]汪耀明, 潘升东, 徐铜文. 电渗析技术在木糖醇酸水解法制备中的应用[J]. 化工学报,2015, 66(9): 3529-3534.
[14]赵宗良, 郭红霞, 林育群, 等. 高浓度硝酸溶液的扩散渗析过程研究[J]. 膜科学与技术,2022, 42(1): 110-114.
[15]孙帅, 孙宏骞, 宋静, 等. 动态扩散渗析法回收盐酸的实验与模型分析[J]. 过程工程学报,2021, 21(1): 57-63.
[16]Sarkar S, Hossain S M, Sharma R, et al. Harnessing imidazole containing crosslinked AEM for HCl resurrection from industrial spent effluent by integrated diffusion dialysis and electrodialysis: Effect of small and macromolecular crosslinker[J]. Chem Eng J, 2023, 477: 147009.
[17]Xue S, Wu C, Wu Y, et al. An optimized process for treating sodium acetate waste residue: Coupling of diffusion dialysis or electrodialysis with bipolar membrane electrodialysis[J]. Chem Eng Res Des, 2018, 129: 237-247.
[18]Gueccia R, Randazzo S, Martino D C, et al. Experimental investigation and modeling of diffusion dialysis for HCl recovery from waste pickling solution[J]. J Environ Manage, 2019, 235: 202-212.
[19]těpánek V, Palat Z, Bendová H. Modeling and numerical analysis of counter-current dialyzer with chemical reaction in stripping solution[J]. Chem Eng Sci, 2020, 221: 115641.
[20]严家辉,何松,王珺瑶,等.基于火用生命周期分析的直接空气碳捕集技术可持续性研究[J/OL].中国环境科学,1-12[2025-09-24].https://doi.org/10.19674/j.cnki.issn1000-6923.20250801.003.
[21]Mirkhalafi S, Mohammadnezhad B, Mousazadehgavan M, et al. Technical and environmental sustainability of pharmaceutical wastewater treatment using Ce-NaY zeolite-modified polyethersulfone (PES) membranes: A life cycle assessment approach[J]. ACS ES&T Water, 2025, 5(7): 3818-3830.
[22]Wang R, Xue J, Meng X, et al. Separation of lithium and imidazolium ions by monovalent selective cation exchange membrane[J]. Sep Purif Technol, 2025, 370: 133333.
[23]Caccamo M T, Magazù S. Investigation of glucose-water mixtures as a function of concentration and temperature by infrared spectroscopy[J]. Int J Mol Sci, 2023, 24(3): 2564.
[24]李碧珠, 徐正康, 叶晓蕾, 等. 葡萄糖浆在不同影响因素下的粘度特性研究[J]. 食品工程,2018, (1): 53-55.
[25]Ren H, Wang Q, Zhang X, et al. Membrane fouling caused by amino acid and calcium during bipolar membrane electrodialysis[J]. J Chem Technol Biotechnol, 2008, 83(11): 1551-1557.
[26]Kienberger M, Weinzettl C, Leitner V, et al. (Selective) Isolation of acetic acid and lactic acid from heterogeneous fermentation of xylose and glucose[J]. Chem Eng J Adv, 2023, 16: 100552.
[27]Palat Z, Bendová H. Continuous dialysis of sulphuric acid and sodium sulphate mixture[J]. J Membr Sci, 2016, 497: 36-46.
[28]李传润, 王虎传, 张旭, 等. 扩散渗析法回收精氨酸生产中的盐酸[J]. 膜科学与技术,2012, 32(4): 102-106.
[29]Ciocirlan O, Brinzei M, Stefaniu A. Solvation behavior of chitosan monomers in aqueous [Hmim]Cl solutions. Experimental and DFT studies[J]. J Mol Liq,2024, 41: 125878.
[30]刘娇, 丁亮, 吴亮, 等. 电场辅助制备分层多孔扩散渗析膜[J]. 膜科学与技术,2019, 39(3): 70-78.
[31]Wang R, Wang Q, Wang Y, et al. Insights into the transport mechanism of acidic amino acids across a cation-exchange membrane: Glutamate as a case study[J]. J Membr Sci, 2025, 718: 123666.
[32]vila-Avilés R D. Quantum chemical analysis of isomerization and protonation of amino group in D-glucosamine[J]. MRS Commun, 2023, 13(6): 1303-1308.
[33]Wang W, Zhang Y, Wang C, et al. Simultaneous manipulation of membrane enthalpy and entropy barriers towards superior ion separations[J]. Angew Chem Int Ed, 2024, 63(37): e202408963.
[34]Naik N S, Nellur U, Nagaraja K K, et al. Mechanism underlying anion-sieving in poly(ionic liquid)-based membrane: Effective acid recovery from engineering waste[J]. J Membr Sci, 2025, 713: 123349.
[35]周培根,尤瑜敏,戚晓玉,等. 氨基葡萄糖盐酸盐的制备及其某些性质[J]. 水产学报,2000, (1): 76-80.
[36]Nare bska A, Kurantowicz M, Staniszewski M. Separation of fermentation products by membrane techniques. Ⅳ. Electrodialytic conversion of carboxylates to carboxylic acids[J]. Sep Sci Technol, 2001, 36(3): 443-455.
[37]Mancini E, Ramin P, Styrbck P, et al. Separation of succinic acid from fermentation broth: Dielectric exclusion, Donnan effect and diffusion as the most influential mass transfer mechanisms[J]. Sep Purif Technol, 2022, 281: 119904.
[38]李斌玉, 赵有璟, 王敏, 等. 电渗析离子交换膜污染机理及控制策略[J]. 化工进展,2025, 44(10): 5532-5546.
[39]Phukan R, Guttierez L, De Schepper W, et al. Short term fouling tests on homogeneous and heterogeneous anion-exchange membranes from food and bio-based industrial streams: Foulant identification and characterization[J]. Sep Purif Technol, 2023, 322: 124247.
[40]Zhao Z, Shi S, Cao H, et al. Comparative studies on fouling of homogeneous anion exchange membranes by different structured organics in electrodialysis[J]. J Environ Sci, 2019, 77: 218-228.
[41]Meng J, Shi L, Wang S, et al. Membrane fouling during nutrient recovery from digestate using electrodialysis: Impacts of the molecular size of dissolved organic matter[J]. J Membr Sci,2023, 685: 121974.
[42]Suhag S, Kumar P, Mandal J R, et al. Functionalized graphene oxide-modified sulfonated poly(2,6-dimethyl-1,4-phenylene oxide) based thermal-resistance anti-fouling bi-functional cation exchange membrane for electrodialytic desalination[J]. Desalination, 2024, 578: 117454.
[43]Ding W T, Huo H Q, Sun D, et al. Surface implantation of ionically conductive polyhydro-xyethylaniline on cation exchange membrane for efficient heavy metal ions separation[J]. J Environ Chem,2024, 12(1): 111760.
[44]Persico M, Mikhaylin S, Doyen A, et al. Formation of peptide layers and adsorption mechanisms on a negatively charged cation-exchange membrane[J]. J Colloid Interface,2017, 508: 488-499.
[45]Bukhovets A, Eliseeva T, Oren Y. Fouling of anion-exchange membranes in electrodialysis of aromatic amino acid solution[J]. J Membr Sci, 2010, 364(1): 339-343.
[46]Chen J, Dai R, Wang Z. Closing the loop of membranes by recycling end-of-life membranes: Comparative life cycle assessment and economic analysis[J]. Resour Conserv Recycl, 2023, 198: 107153.
[47]Xue N, Lu J, Gu D, et al. Carbon footprint analysis and carbon neutrality potential of desalination by electrodialysis for different applications[J]. Water Res, 2023, 232: 119716.
[48]Alrashidi A, Aleisa E, Alshayji K. Life cycle assessment of hybrid electrodialysis and reverse osmosis seawater desalination systems[J]. Desalination, 2024, 578: 117448.

Service：

【Download】【Collect】

《膜科学与技术》编辑部 Address: Bluestar building, 19 east beisanhuan road, chaoyang district, Beijing; 100029 Postal code; Telephone：010-80492417/010-80485372; Fax：010-80485372 ; Email：mkxyjs@163.com