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微流控技术构建单分散微囊膜的研究新进展

作者：褚良银?，谢锐，巨晓洁，刘丽，汪伟

单位：四川大学化学工程学院

关键词：微囊膜；控制释放；微流控；单分散

DOI号：

分类号： TQ028.8

出版年,卷(期):页码： 2011,31(3):59-63

摘要：

单分散微囊膜在控制释放领域显示出许多优势而备受重视，而近期出现的微流控技术为制备单分散微囊膜提供了可靠的新方法。本文综述了微流控技术构建单分散微囊膜的研究新进展，着重介绍了微流控技术制备基于乙基纤维素、壳聚糖和海藻酸钙等生物相容性材料的单分散微囊膜以及基于聚N-异丙基丙烯酰胺的温敏型和离子识别型的单分散微囊膜的研究现状。

Monodisperse microcapsule membranes are getting more and more attentions because of their numerous advantages in the field of controlled release. The microfluidic technique provides a novel solid method for generating monodisperse microcapsule membranes. The recent progresses of fabrications of monodisperse microcapsule membranes using microfluidic techniques were reviewed. Especially, the microfluidic preparations of monodisperse microcapsules with ethyl cellulose membranes, chitosan membranes, alginate membranes, poly(N-isopropylacrylamide)-based thermo-responsive membranes and ion-recognizable membranes were introduced.

基金项目：

国家973计划（2009CB623407）; 国家自然科学基金（20825622, 20806049, 20990220, 20906064, 21076127, 21036002）; 教育部高等学校博士学科点专项科研基金(200806100038, 200806101045, 20090181120045)和四川省青年科技基金（08ZQ026-042）

作者简介：

褚良银（1967-），男，湖北五峰人，教育部长江学者特聘教授，主要从事膜材料与控释系统研究。Email: chuly@scu.edu.cn

参考文献：

[1] 马光辉，苏志国. 高分子微球材料[M]. 北京：化学工业出版社，2005：1.
[2] Nie Z, Xu S, Seo M, Lewis PC, Kumacheva E. Polymer particles with various shapes and morphologies produced in continuous microfluidic reactors [J]. Journal of American Chemical Society, 2005, 127(22): 8058-8063.
[3] Liu L, Yang JP, Ju XJ, Xie R, Yang L, Liang B, Chu LY. Microfluidic preparation of monodisperse ethyl cellulose hollow microcapsules with non-toxic solvent [J]. Journal of Colloid and Interface Science, 2009, 336(1): 100-106.
[4] Liu L, Yang JP, Ju XJ, Xie R, Liu YM, Wang W, Zhang JJ, Niu CH, Chu LY. Monodisperse core-shell chitosan microcapsules for pH-responsive burst release of hydrophobic drugs [J]. Soft Matter, 20102011, 6(16): 3759-3763., submitted DOI:10.1039/C0SM01393E.
[5] Ren PW, Ju XJ, Xie R, Chu LY. Monodisperse alginate microcapsules with oil core generated from a microfluidic device [J]. Journal of Colloid and Interface Science, 2010, 343(1): 392-395.
[6] Wang W, Liu L, Ju XJ, Zerrouki D, Xie R, Yang L, Chu LY. A novel thermo-induced self-bursting microcapsule with magnetic-targeting property [J]. ChemPhysChem, 2009, 10(14): 2405-2409.
[7] Pi SW, Ju XJ, Wu HG, Xie R, Chu LY. Smart responsive microcapsules capable of recognizing heavy metal ions [J]. Journal of Colloid and Interface Science, 2010, 349(2): 512-518.
[8] Chu LY, Utada AS, Shah RK, Kim JW, Weitz DA. Controllable monodisperse multiple emulsions [J]. Angewandte Chemie International Edition, 2007, 46(47): 8970-8974.
[9] Liu L, Wang W, Ju XJ, Xie R, Chu LY. Smart thermo-triggered squirting capsules for nanoparticle delivery [J]. Soft Matter, 2010, 6(16): 3759-3763.

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