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多巴胺的自聚-附着行为与膜表面功能化

作者：徐又一，蒋金泓，朱利平，朱宝库

单位：浙江大学高分子科学与工程学系，高分子合成与功能构造教育部重点实验室，

关键词：多巴胺；多巴；儿茶酚衍生物；功能化；仿生；表面改性

DOI号：

分类号： TQQ028.8

出版年,卷(期):页码： 2011,31(3):32-38

摘要：

多巴胺（dopamine）是一种生物神经递质，在水溶液条件下，它能在溶解氧的作用下发生氧化-交联反应，形成强力附着于固体材料表面的聚多巴胺复合薄层。基于多巴胺的这一特性，近年来膜技术研究者们通过多巴胺在固体基膜上的自聚-复合，对膜进行表面改性，并以具有反应活性的聚多巴胺复合层为平台，对膜进行进一步的表面修饰，实现膜的功能化。本文论述了多巴胺在膜表面修饰与功能化方面的研究进展，应用领域包括超/微滤膜、生物医用膜以及渗透汽化膜等。

Dopamine is a kind of biological neurotransmitter. In aqueous solution, it can be oxidized by dissolved oxygen and undergoes an oxidation-crosslinking reaction, forming a composite layer of polydopamine that strongly attaches to a substrate. Based on the characteristics of dopamine, in recent years, membrane technology researchers have performed surface modification via the self-polymerization-composite of dopamine on solid basement-membranes. Besides, the polydopamine composite layer with high reactivity offers a platform for further surface modification and functionalization. In this paper, research progress on modification and functionalization of membrane surface using dopamine was reviewed, the application fields included ultra/micro filtration, biomedical membranes and pervaporation film, etc.

基金项目：

国家“973”计划项目（2009CB623402），国家自然科学基金项目（50803054），浙江省自然科学基金项目（Y4100204）资助

作者简介：

徐又一（1945-），男，上海人，教授，从事高分子膜材料与技术研究. *通讯作者：徐又一（Email: opl-yyxu@zju.edu.cn）

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