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膜式氧合器中聚砜非对称膜的制备及表征

作者：吕权¹，殷海燕¹，虞文魁²，黄鑫¹，李磊¹

单位： 1、南京大学化学化工学院, 江苏南京　210093，2、南京大学医学院，江苏南京　210093

关键词：聚砜膜式氧合器；渗透通量；临界透水压力；传输效率

DOI号：

分类号： TB324

出版年,卷(期):页码： 2013,33(5):25-29

摘要：

通过浸没沉淀相转换法制备了膜式氧合器的聚砜不对称膜，并对其性能进行表征。制膜实验结果表明，随着铸膜液浓度的增加，氧气和二氧化碳渗透通量减小，临界透水压力增大，而湿膜的预挥发时间越长，膜的通量越小，但是临界透水压力变化不大，因此优化的铸膜液浓度为15%和预挥发时间为5s。此外针对膜式氧合器的气液传输测试结果表明，当牛血流速为5L/min时，氧气和二氧化碳通过膜的传输速率分别达到163ml/min和148ml/min，可以满足膜式氧合器气体交换传输能力的要求。

Membrane oxygenator-oriented polysulfone(PSF) asymmetric membranes were prepared by wet phase inversion method and their performance was characterized primarily. It was demonstrated through experiments of membranes preparation that with increasing PSF concentration of casting solution, permeation flux of O2 and CO2 decreased and critical water permeability pressure of membrane（CWPPM） increased. Moreover, prolonging pre-volatilization time of wet membranes had a disadvantage on gas permeation but had little effect on CWPPM. Accordingly, the optimal PSF concentration of casting solution and pre-volatilization time of wet membranes is 15% and 5s, respectively. Besides, application experimental results of gas-liquid transport through PSF membrane oxygenator indicated that when the flow rate of bovine blood reached 1.5L/min, permeation flux of O2 and CO2 were 163ml/min and 148ml/min, respectively, which could achieve the gas exchange transmission capacity of membrane oxygenator.

基金项目：

江苏省自然科学基金面上项目（BK2012727）

作者简介：

吕权（1987—），男，河南省信阳市人，硕士研究生，研究方向为人工肺用膜材料；李磊，男，副教授，通讯联系人，电话: ( 025 ) 83596665- 810, E-mail：ll-nju@163.com.

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