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MoS2@SiO2纳米纤维的制备及抗菌性能研究

作者：李雪梅，崔红圆，郭勤，朱泽阳，张宇

单位：新疆理工学院新疆新能源与储能技术重点实验室，阿克苏 843100

关键词： MoS2； SiO2纳米纤维；抗菌材料；静电纺丝

DOI号： 10.16159/j.cnki.issn1007-8924.2025.02.008

分类号： TQ427.26; TB332

出版年,卷(期):页码： 2025,45(2):65-74

摘要：

当前各类微生物污染越发严重及普遍，新型抗菌材料的研究可成为解决该问题的重要途径。基于此，本文构建了一种具有特殊结构和优异抗菌性能的界面，首先以硅酸四乙酯（TEOS）为硅源，利用静电纺丝技术制备得到SiO2纳米纤维；其次通过原位负载法将二硫化钼（MoS2）负载到SiO2纳米纤维上，由此制备得到MoS2@SiO2纳米纤维，并对其组成成分、形貌结构、抗菌活性以及生物相容性进行分析。结果表明：MoS2@SiO2纳米纤维在15 min内就可以表现出优异的抗菌活性，经过24 h培养后，MoS2@SiO2纳米纤维对大肠杆菌和金黄色葡萄球菌显示出持久、广谱的抗菌性能。而且经过10次洗涤后，MoS2@SiO2纳米纤维依旧维持较好的抗菌活性。另外，800.0 mg/mL的MoS2@SiO2纳米纤维分散液与L929细胞混合培养后显示出较低的细胞毒性。本研究为SiO2纳米纤维的研究提供了一定的研究基础，进一步拓宽了纯无机抗菌纤维的应用市场。

At present, all kinds of microbial contamination is more and more seious and common, and the research of new antibacterial materials become a major approach to solve the problem. Based on this, in this study, an interface with special structure and excellent antibacterial properties was constructed. Firstly, SiO2 nanofibers were prepared by electrospinning using tetraethyl orthosilicate (TEOS) as silicon source. Secondly, molybdenum disulfide (MoS2) was loaded onto SiO2 nanofibers by in-situ loading method through hydrothermal reaction, and MoS2@SiO2 nanofibers were prepared. The composition, morphology, antibacterial activity and biocompatibility were analyzed. The results showed that MoS2@SiO2 nanofibers exhibited excellent antibacterial activity within 15 min, and after 24 h culture, MoS2@SiO2 nanofibers showed long-lasting and broad-spectrum antibacterial properties against E. coli and S. aureus. After 10 times of washing, MoS2@SiO2 nanofibers still maintained good antibacterial activity. In addition, 800.0 mg/mL MoS2@SiO2 nanofibers dispersion showed low cytotoxicity and good biocompatibility with L929 cells. Therefore, this study provides a certain research basis for the study of SiO2 nanofibers, and further broadens the application market of pure inorganic antibacterial fibers.

基金项目：

新疆维吾尔自治区自然科学计划（自然科学基金）青年科学基金项目（2022D01C352）；新疆维吾尔自治区大学生创新创业训练计划项目（202313558006、S202413558014、202413558001）

作者简介：

李雪梅（1994-），女，甘肃张掖人，讲师，研究方向为无机功能纳米纤维膜的制备及应用

参考文献：

[1]Yu X, Huang K, Zhang Y, et al. Photodynamically functionalized CoP/MoS2 nanocomposites with antibacterial activity[J]. ACS Appl Nano Mater, 2024, 7(3): 3260-3268.
[2]Al Ohaly R, Benoit M E, Schuster M G. Infectious diseases: what you may have missed in 2022[J]. Ann Intern Med, 2023, 176(5): 701-717.
[3]Murray C J L, Ikuta K S, Sharara F, et al. Global burden of bacterial antimicrobial resistance in 2019: A systematic analysis[J]. The lancet, 2022, 399(10325): 629-655.
[4]Wang Q, Ji P, Yao Y, et al. Gliadin-mediated green preparation of hybrid zinc oxide nanospheres with antibacterial activity and low toxicity[J]. Sci Rep, 2021, 11(1): 10373.
[5]Hoang T D, Nguyen T C, Doan T T, et al. Preparation and photocatalytic and antibacterial properties of polyvinyl alcohol/chitosan/TiO2@Ag electrospun nanofibers[J]. Thin Solid Films, 2024, 797: 140344.
[6]Sargazi G, Afzali D, Mostafavi A, et al. Synthesis of CS/PVA biodegradable composite nanofibers as a microporous material with well controllable procedure through electrospinning[J]. J Polym Environ, 2018, 26: 1804-1817.
[7]Le T T, Nguyen T V, Nguyen T A, et al. Thermal, mechanical and antibacterial properties of water-based acrylic polymer/SiO2-Ag nanocomposite coating[J]. Mater Chem Phys, 2019, 232: 362-366.
[8]Wan M, Zhao H, Peng L, et al. Facile one-step deposition of Ag nanoparticles on SiO2 electrospun nanofiber surfaces for label-free SERS detection and antibacterial dressing[J]. ACS Appl Bio Mater, 2021, 4: 6549-6557.
[9]Yuan Y, Guo R, Hong L, et al. Recent advances and perspectives of MoS2-based materials for photocatalytic dyes degradation: a review[J]. Colloid and Surface A, 2021, 611: 125836.
[10]Xu J, Cai R, Zhang Y, et al. Molybdenum disulfide-based materials with enzyme-like characteristics for biological applications[J]. Colloid and Surface B, 2021, 200: 111575.
[11]Wan M, Zhao H, Peng L, et al. Facile one-step deposition of Ag nanoparticles on SiO2 electrospun nanofiber surfaces for label-free SERS detection and antibacterial dressing[J]. ACS Appl Bio Mater, 2021, 4(8): 6549-6557.
[12]Zhao J, Zhang Z, Yang S, et al. Facile synthesis of MoS2 nanosheet-silver nanoparticles composite for surface enhanced Raman scattering and electrochemical activity[J]. J Alloy Compd, 2013, 559: 87-91.
[13]Meng H, Pan X, Li X, et al. Oil-water separation performance and thermoregeneration of a nanofibrous SiO2 membrane prepared by sol-electrospinning[J]. Chem Select, 2023, 8(29): e202300694.
[14]Fu X, Wu H, Liu Z, et al. MoS2 nanosheets as substrates for SERS-based sensing[J]. ACS Appl Nano Mater, 2024, 7(4): 3988-3996.
[15]Liu J, He Z W, Bai G, et al. Fabrication of novel water glass-based monolithic aerogels with fibrous skeleton under alkaline for oil sorption and thermal evaporation[J]. J Non-Cryst Solids, 2023, 611: 122349.
[16]Wang J W, Xun Fang X, Chen H H, et al. Antibacterial properties of the flower shaped nano-CuFe2O4@MoS2 composites [J]. Colloids and Surfaces A, 2024, 683:133076.
[17]Lin H, Chen X, Li H, et al. Hydrothermal synthesis and characterization of MoS2 nanorods[J]. Mater Lett, 2010, 64(15): 1748-1750.
[18]Khalid S, Gao A, Wang G, et al. Tuning surface topographies on biomaterials to control bacterial infection[J]. Biomater Sci, 2020, 8(24): 6840-6857.
[19]Zhang D, Li X, Liang T, et al. Construction of antibacterial fabrics with polymer cationic broccolo-shaped nanoparticles[J]. Polym Adv Technol, 2022, 33(12): 4012-4022.
[20]Halder S, Yadav K K, Sarkar R, et al. Alteration of Zeta potential and membrane permeability in bacteria: A study with cationic agents[J]. SpringerPlus, 2015, 4: 1-14.
[21]Wang X L, Li Y, Huang J, et al. Efficiency and mechanism of adsorption of low concentration uranium in water by extracellular polymeric substances[J]. J Environ Radioactiv, 2019, 197: 81-89.
[22]Xu C, Wang X, Cao L, et al. Highly sensitive and antibacterial flexible bilayer strain biosensor for human motion monitoring[J]. Ind Crop Prod, 2024, 21: 118081.
[23]Gnoumou E, Tran T T A, Srinophakun P, et al. Optimization of lysozyme-modiffed ion exchange nanoffber membrane for efffcient capture of Escherichia coli: Antibacterial and cytotoxic studies[J]. J Taiwan Inst Chem E, 2024, 157: 105400.

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